Deposition of BACE-1 Protein in the Brains of APP/PS1 Double Transgenic Mice
نویسندگان
چکیده
منابع مشابه
Deposition of BACE-1 Protein in the Brains of APP/PS1 Double Transgenic Mice
The main causes of Alzheimer's disease remain elusive. Previous data have implicated the BACE-1 protein as a central player in the pathogenesis of Alzheimer's disease. However, many inhibitors of BACE-1 have failed during preclinical and clinical trials for AD treatment. Therefore, uncovering the exact role of BACE-1 in AD may have significant impact on the future development of therapeutic age...
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ژورنال
عنوان ژورنال: BioMed Research International
سال: 2016
ISSN: 2314-6133,2314-6141
DOI: 10.1155/2016/8380618